Testosterone Undecanoate Intramuscular Reviews and User Ratings: Effectiveness, Ease of Use, and Satisfaction

In case of treatment continuation, further measures should be taken to minimise the individual VTE risk. In patients suffering from severe cardiac, hepatic or renal insufficiency or ischaemic heart disease, treatment with testosterone may cause severe complications characterised by oedema with or without congestive cardiac failure. If severe upper abdominal complaints, liver enlargement or signs of intra-abdominal haemorrhage occur in men using Nebido, a liver tumour should be included in the differential-diagnostic considerations. If you are suffering from severe heart, liver or kidney disease,treatment with Nebido may cause severe complications in the form of water retention in your body sometimes accompanied by (congestive) heart failure.

Our Treatments

If you are experiencing any combination of these symptoms, you may have low testosterone and need treatment. One of the best ways to address this condition is with testosterone replacement therapy, which has been known to help men all across the country fight the symptoms of low testosterone. At cold storage temperatures the properties of this oil-based solution might temporarily change (e.g. higher viscosity, cloudiness).

With this loading dose, sufficient steady state testosterone levels may be achieved more rapidly. In 2013, a study aimed to evaluate the efficacy of testosterone undecanoate therapy on bone mineral density (BMD) and biochemical markers of bone turnover in elderly males with osteoporosis and low serum testosterone levels. Nebido is an intramuscularly administered depot preparation of testosterone undecanoate and thus circumvents the first-pass effect. Following intramuscular injection of testosterone undecanoate as an oily solution, the compound is gradually released from the depot and is almost completely cleaved by serum esterases into testosterone and undecanoic acid.

Testosterone Nebido costs UK

There is no data available on the use of Nebido in males under 18 years of age. You may have low testosterone depending on the symptoms you have, please contact us to find out how we can help. References, sources and studies used alongside our own in-house research have https://volkatv-officiel.com/exploring-the-effects-of-anabolic-drugs-on-muscle-9/ been cited below, most of which contain external clickable links to reviewed scientific paper that contain date stamped evidence. There is a pre-scored mark beneath the coloured point on the ampoule eliminating the need to file the neck.

This is usually done in the ventrogluteals, deltoid, or another dense muscle area. The Nebido type of injection is very strong and will last for a while, making it more convenient to use Nebido injections than some other types of TRT injections. Caution should be exercised in patients predisposed to oedema, e.g. in case of severe cardiac, hepatic, or renal insufficiency or ischaemic heart disease, as treatment with androgens may result in increased retention of sodium and water. In case of severe complications characterized by oedema with or without congestive heart failure treatment must be stopped immediately (see section 4.8).

Medical uses

• Following the use of hormonal substances such as androgen compounds, cases of benign (non-cancerous) and malignant (cancerous) liver tumours have been observed to occur.
• The active substance is testosterone undecanoate 250 mg/ml (corresponding to 157.9 mg testosterone).
• (For the ampoule see section 6.6 for instructions on opening the ampoule safely).
• Testosterone which is generated by ester cleavage from testosterone undecanoate is metabolised and excreted the same way as endogenous testosterone.
• The next stage in the Nebido injection treatment is to achieve and maintain normal testosterone levels after the initial injections.
• Contact your medical professional immediately to learn if it is still safe for you to be taking Nebido injections and whether you can still benefit from it.

Sex hormones are known to facilitate the development of certain tumours induced by known carcinogenic agents. Toxicological studies have not revealed other effects than those which can be explained based on the hormone profile of Nebido. Testosterone which is generated by ester cleavage from testosterone undecanoate is metabolised and excreted the same way as endogenous testosterone. The undecanoic acid is metabolised by ß -oxidation in the same way as other aliphatic carboxylic acids. The major active metabolites of testosterone are oestradiol and dihydrotestosterone.

With properly-administered Nebido treatments, you will only have to receive an injection every 10 to 14 weeks. This timeframe and wide period of time between two injections make it a highly desirable treatment and the reason that many people choose Nebido injections when it comes time to treat their low testosterone. To start the treatment, your doctor or medical professional will administer Nebido slowly into one of the muscles in the body.